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Is this a melodica solo? Probably. Can it be played on harmonica?
Definitely.

5+ 6+ 5+   6- 5+ 4- 5+    5- 6+ 5- 4- 5+ 4- 4+
4-

5+ 6+ 5+ 6- 5+ 4- 5+     5- 5+ 4- 4+ 3-"

Side note: The guitar solos are in g minor, so if you want to play
in cross, you don't have to switch harps.